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KMID : 0371619920080010115
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Journal of Wonkwang Medical Science
1992 Volume.8 No. 1 p.115 ~ p.126
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Prospective Study for Prevention of Thrombophlebitis of Thrombophlebitis of Indwelling Central Venous Catheters
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Abstract
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The placement of catheter in a central vein is a well established procedure for infusing fluid or measuring central venous pressure. The catheter related complication such as thrombophlebitis as sepsis have been well known.
Several techniques have been used in an effort to minimize these complications, but none have gained the wide acceptance. The author, therefore, studied the influence of antiphlebitic mixture of heparin and hydrocortisone on the catheter-related
complications in a group of hospitalized patients.
The patients were randomly divided into two groups the patients of control group were not administered antiphlebitic mixture. The patients of study group were given 1000 units of heparin and 5mg of hydrocortisone added in each 100㎖intravenous
infusate.
@ES The results were as follows:
@EN 1. The maintenance time of catheter was 13.6±7.5 days in the study group and 8.1±3.7 days in the control group.
2. The thrombophlebitis was the most common reason for removal of catheter in two groups.
3. The mixture of antiphlebitic mixture resulted in the prolongation of the number of thrombophlebitis-free time, significant reduction in the grade of thrombophlebitis and reduction in positive culture rate of the catheter tips.
4. No significant differences in white blood cell count, platelet count, prothrombin time and partial thromboplastin time throughout the study period were observed between the two groups.
5. The antiphlebitic mixture-induced complication didn's occur during the therapy.
In conclusion, use of the antiphlebitic mixture(heparin and hydrocortisone) is recommendable policy to reduce the incidence of catheter related complication.
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